WebMar 21, 2007 · Grapefruit Juice. One of the most well known food–drug interactions is grapefruit juice and the HMG-CoA reductase inhibitors, more commonly known as statins. Grapefruit juice, in large quantities (32 oz. or more per day), can inhibit the cytochrome P450 3A4 (CYP3A4) enzyme and increase blood levels of drugs metabolized by this … WebAssessing knowledge of drug-food interactions and associated factors among HCPs working in public hospitals in Ethiopia ... CYP3A4 metabolism of simvastatin inhibited by grapefruit juice, and lithium and sodium competing for tubular reabsorption in the kidney are examples of pharmacokinetic interactions. On the other hand, pharmacodynamic ...
Can I Take Benicar & Eat Grapefruit? Healthfully
WebDec 30, 2024 · Side effects from grapefruit-statin interaction are typically mild, such as increase in muscle and joint pain. Severe side effects are rare, but can include muscle … With most drugs that are affected by grapefruit juice, “the juice lets more of the drug enter the blood,” says Shiew Mei Huang, Ph.D., of the FDA. “When there is too much drug in the blood, you may have more side effects.” For example, if you drink a lot of grapefruit juice while taking certain statin drugs to lower … See more When drugs are swallowed, they may be broken down (metabolized) by enzymes and/or absorbed using transporters in cells found in the small … See more literature cited format
Which Medications Interact With Grapefruit Juice? - Verywell Health
WebSome medicines used in the treatment of cancers may interact with grapefruit juice. You should check with your doctor before drinking grapefruit juice. Other medicines. This list … WebJan 15, 2024 · Adverse drug interactions due to grapefruit juice are well known prompting warnings even in drug labels. Similar issues have not been reported for clementines and available data is scarce, despite of genetic descent. ... Our data indicate that clementine juice similar to grapefruit juice bears the potential for profound interactions with drugs ... WebAug 22, 2024 · 11 atorvastatin interactions to know about. Atorvastatin has many possible interactions. Here, we'll review some notable ones you should know about. Keep in mind that this list doesn’t include all possible atorvastatin interactions. 1. Grapefruit and grapefruit juice. Grapefruit and grapefruit juice can literature cited in research