Tacstd2

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August undefined, 2024

WebMay function as a growth factor receptor. This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009] WebApr 21, 2024 · Tumor Associated Calcium Signal Transducer 2 (TACSTD2) is a transmembrane glycoprotein which is involved in fetal organogenesis, cell proliferation and cell migration via different molecular pathways [ 18] and is part of the GA733–2 family.

TACSTD2 Gene - GeneCards TACD2 Protein TACD2 Antibody

WebTACSTD2, tumor associated calcium signal transducer 2 Vertebrate Orthologs 3 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog TACSTD2, tumor associated calcium signal transducer 2. Synonyms EGP1, EGP-1, GA7331, GA733-1, GP50, M1S1, TROP2 ... WebSequence. Sequence: Please enter your sequence in the 5' to 3' direction. Sequences must be composed solely of the nucleotides A, C, G, T. Please convert U's to T's and remove any spaces, tabs, or line breaks. Sequence: Sequences must be composed solely of the nucleotides A, C, G, and U. X Remove All. briggs and stratton engine oil requirements

4070 - Gene ResultTACSTD2 tumor associated calcium signal transducer 2 [ (human)]

WebNov 26, 2015 · Generally, the TACSTD2 molecule is composed of five main regions: (1) a signal sequence (located at amino acid (aa) 1–26), (2) an epidermal growth factor-like … WebMar 14, 2024 · TACSTD2 is an intronless gene encoding a type-I cell-surface glycoprotein that functions as an intracellular calcium signal transducer [ 24] and is dysregulated in many epithelial cancers [ 25 – 27 ]. TACSTD2 has previously been reported to impact the cellular localization of CLDN1 and OCLN in human corneal epithelial cells [ 21 ]. WebMar 25, 2005 · The TACSTD2 gene encodes a type I transmembrane protein with a structure consistent with a cell signal transduction function (summary by Ren et al., 2002). Cloning … briggs and stratton engine parts 12h702

Human TROP-2 / TACSTD2 Protein, His Tag (MALS verified

WebJul 11, 2024 · The only known homolog of EPCAM, TROP2 (also known as tumor-associated calcium signal transducer 2, TACSTD2), shares 49% sequence identity and 67% sequence similarity with EPCAM, and, like EPCAM, is expressed in a wide range of epithelia ( Stepan et al., 2011; Trerotola et al., 2013 ). WebBy using single cell transcriptome analysis, we have identified TROP2 (encoded by Tacstd2) and FOXA2 as reliable markers of luminal and glandular compartments, respectively. Our lineage trajectory predictions, organoid formation and lineage tracing experiments suggest that both luminal and glandular epithelium contain stem/progenitor cells. briggs and stratton engine oil caphttp://www.cancerindex.org/geneweb/M1S1.htm briggs and stratton engine owners manual

"WebOct 18, 2024 · The proposed MPs such as P-glycoprotein-1 (Pgp-1), Her2/Erb-b2 receptor tyrosine kinase 2, tumour-associated calcium-signal transducer 2 protein (TACSTD2), vascular endothelial growth factor receptor 1 (VEGFR1), and others were not only valuable for the diagnosis of BC but could also facilitate and improve clinical outcomes in multiple … " - Tacstd2

Tacstd2

Web在tnbc患者队列（n=360）的多组学数据中[2]，研究人员发现erbb2基因（编码her2蛋白）的表达在lar亚型中高于其他亚型，而lar和blis亚型患者tacstd2基因（编码trop-2蛋白）表达高于im和mes亚型患者。 WebData indicating that the tumor-associated calcium signal transducer 2 ( TACSTD2) protein may protect CLDN1 and 7 proteins from protein degradation by the ubiquitin-proteasome system. Top, HeLa cells were introduced with CLDN1, 4, or 7 genes with or without the TACSTD2 gene.

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WebG0S2 reduced genes associated with an epithelial phenotype, especially in ER- cells, including CDH1, ELF3, STEAP4 and TACSTD2 suggesting promotion of the epithelial-mesenchymal transition (EMT). G0S2 also repressed estrogen signaling and estrogen receptor target gene signatures, especially in ER+ cells, including TFF1 and TFF3. ... WebOct 8, 2024 · Trop2由 TACSTD2 基因编码，是一种跨膜糖蛋白，可作为细胞内钙信号转导器。Trop2在许多正常组织中表达，如子宫、皮肤、食道、膀胱、口腔黏膜、鼻咽和肺。

WebTROP2/TACSTD2/TROP-2 IL17A/CTLA-8/IL-17 CD279/PD1/hSLE1 CD200R1/CRTR2/MOX2R CCR8/CCR-8/CDw198 more... Super-Affinity Bioreagents DNA/RNA Antibody Antibodies against Small Molecule Polyethylene glycol (PEG) antibody Phosphorylated Antibody Tag Antibody Allergens and Antibodies Isotype Control Antibody WebApr 14, 2024 · TROP-2 is also known as tumor associated calcium signal transducer 2 (TACSTD2), which is a cell surface glycoprotein functioning as a transmembrane …

WebMechanistic studies suggest that TACSTD2 is involved in the phosphorylation of CLDN1 and OCLN, which is required for their proper cellular localization. Silencing of TACSTD2 dramatically inhibits HCV infection with a pan-genotype effect that … WebApr 14, 2024 · Abstract. Background: Trophoblast cell-surface antigen 2 (Trop-2) is known as tumor-associated calcium signal transducer 2 (TACSTD2) and plays a role in tumor progression, given its active interplay with several key molecular pathways associated with cancer development and progression. DB-1305 is a Trop-2 antibody-drug conjugate (ADC) …

WebTACSTD2 Gene, Drug Resistance, Tissue Distribution, Mutation Distribution, Variants, TACSTD2 Genome Browser, TACSTD2 References. TACSTD2 - Explore an overview of TACSTD2, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data.

WebJun 30, 2024 · TACSTD2 encodes a transmembrane glycoprotein Trop2 commonly overexpressed in carcinomas. While the Trop2 protein was discovered already in 1981 and first antibody-drug conjugate targeting Trop2 were recently approved cancer therapy, the physiological role of Trop2 is still not fully understood. In this article, we show that … briggs and stratton engine mounting boltsWebAug 17, 2024 · Notably, Ck4, Tacstd2 and Sox9 remained specifically expressed in Luminal-C cells (Extended Data Fig. 6f–h,k). These results indicate that these three different luminal cell lineages remained ... briggs and stratton engine oil recommendationWebThe RNA specificity category is based on normalized mRNA expression levels in the consensus dataset, calculated from the RNA expression levels in samples from HPA and … briggs and stratton engine oil 30 weightWebNov 26, 2015 · Generally, the TACSTD2 molecule is composed of five main regions: (1) a signal sequence (located at amino acid (aa) 1–26), (2) an epidermal growth factor-like repeat, (3) a thyroglobulin repeat,... briggs and stratton engine oil specificationsWebSep 6, 2024 · Citations: TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. briggs and stratton engine oil changeWebOct 30, 2024 · Trophoblast Cell Surface Antigen 2 gene (TACSTD2) expression in primary breast cancer. Impact of Spatially Heterogeneous Trop-2 Expression on Prognosis in Oral … briggs and stratton engine only runs on chokeWebCROSS-REFERENCE TO RELATED APPLICATIONS. This application is a Continuation of U.S. patent application Ser. No. 16/649,732, filed Mar. 23, 2024, which is a national stage filing u can you butcher a bull